Basically, markers are particular genomic fragments and used to get information about the function of these genes. Since the production and maturation of sperm cells progress under genetic control, identifying such markers helps us to explain the level and degree of the problem associated with impaired spermatogenesis. Our studies identified a number of important markers helping to manage the treatment of azoospermic patients.
The most problematic cases of infertility are those with unexplained etiology. Approximately 20% of couples are diagnosed with unexplained infertility after a conventional semen analysis. On the other hand oxidative stress is considered to be one of the major causes of male infertility. Oxidative stress is identified sequentially in 4 steps and since each step is related with separate functions of spermatozoa, in the evaluation of unexplained infertility each of these steps should be evaluated by proper tests.
The ideal approach for microTESE should first be to maximize the likelihood of sperm retrieval. And also, in case of no sperm in the intervention, a forward-looking treatment plan should be determined. We call such treatment as the “Multi-dimensional or extended microTESE” model.
You can send your questions to
Prof.Dr. Kaan Aydos
Mahatma Gandhi Caddesi, 19/7 06700 Cankaya, Ankara / TURKEY
+90 312 437 3121 +90 312 508 2258